Key Studies

• Laurent et al. (2009), ZFPIP/Zfp462 is maternally required for proper Xenopus laevis development — PMID: 19111535

• Massé et al. (2010), Involvement of ZFPIP/Zfp462 in chromatin integrity and survival of P19 pluripotent cells — PMID: 20219459

• Massé et al. (2011), ZFPIP/Zfp462 is involved in P19 cell pluripotency and in their neuronal fate — PMID: 21570965

• Wang et al. (2017), Zfp462 deficiency causes anxiety-like behaviors with excessive self-grooming in mice — PMID: 27621227

• Weiss et al. (2017), Haploinsufficiency of ZNF462 is associated with craniofacial anomalies, corpus callosum dysgenesis, ptosis, and developmental delay — PMID: 28513610

• Kruszka et al. (2019), Phenotype delineation of ZNF462 related syndrome — PMID: 31361404

• Yelagandula et al. (2023), ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers — PMID: 36604593

• McConkey et al. (2026), Discovery of a DNA methylation episignature for Weiss-Kruszka syndrome — PMID: 42474752; DOI: 10.1007/s00439-026-02846-1